10% Isitofu se-Enrofloxacin

I-Pharmacodynamics flufenicol sisithinteli-ntsholongwane esibanzi.

Yee-aminools, i-bacteriosuppressor, kwaye isebenza ngokuzibophelela kunye ne-ribosome 50s subunit ukuvimbela ukuhlanganiswa kweeprotheni zebhaktheriya. Inomsebenzi onamandla we-antibacterial ngokuchasene neentlobo zebhaktheriya zegram-positive kunye negram-negative. I-Pasteurella hemolyticus, i-pasteurella multocida kunye ne-actinobacillus suis pleuropneumoniae zazinovelwano kakhulu kwi-flufenicol. I-In vitro, umsebenzi we-antimicrobial we-flufenicol ngokuchasene ne-microorganisms ezininzi ufana okanye womelele kunalowo we-sulfenicol, kwaye ezinye iibhaktheriya ezikwazi ukumelana ne-aminools ngenxa ye-acetylation, njenge-escherichia coli kunye ne-klebsiella pneumoniae, zisenokuba buthathaka kwi-flufenicol.

Isetyenziswa ikakhulu kwizifo zebhaktiriya zehagu, inkukhu kunye nentlanzi ezibangelwa ziibhaktheriya ezibuthathaka, ezifana nezifo zokuphefumla zeenkomo kunye neehagu ezibangelwa yi-pasteurella hemolyticus, pasteurella multocida kunye ne-actinobacillus pleuropneumoniae. I-typhoid kunye ne-paratyphoid ebangelwa yi-salmonella, ikholera yenkukhu, i-dysentery emhlophe yenkukhu, i-colibacillosis, njl.; intlanzi i-pasteurella, i-vibrio, i-staphylococcus aureus, i-hydroomonas, i-enteritis kunye nezinye iibhaktheriya ezibangelwa yi-fish bacterial septicemia, i-enteritis, i-erythroderma kwaye kungekudala.

I-Pharmacokinetics i-flufenicol ixutywa ngokukhawuleza kulawulo lwangaphakathi, kwaye ukuxinwa konyango kunokufikelela kwigazi emva kweyure eli-1, kwaye i-concentration ye-peak yegazi inokufikelela kwi-1 ukuya kwii-3 iiyure. I-bioavailability ingaphezulu kwama-80%. I-Flufenicol isasazwa ngokubanzi kwizilwanyana kwaye inokuwela umqobo wegazi-ubuchopho. Ikhutshwa ikakhulu kumchamo ngendlela yayo yasekuqaleni kunye nexabiso elincinci kwilindle.