I-15% yeSpectinomycin Hydrochloride kunye ne-Lincomycin Hydrochloride Umgubo oNyibilikayo oFakelweyo

I-15% yeSpectinomycin Hydrochloride kunye ne-Lincomycin Hydrochloride Powder eNyibilikayo

Inkcazelo emfutshane:

Amacandelo aphambili: I-Spectinomycin Hydrochloride 10%, i-Lincomycin Hydrochloride 5% kunye ne-carrier carrier.

Amanyathelo okhuseleko: Kuphela ngamantshontsho aneminyaka emi-5 ukuya kwesixhenxe ubudala.

Ixesha lokurhoxisa: akufuneki liqulunqwe.

Inkcazo: 100g Daguanomycin 10g (i-10 yezigidi zeeyunithi) kunye ne-Lincomycin 5g (ngokweC18H34N2O6S).

Inkcazo yokupakisha: 500g / bag.

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Isenzo se-Pharmacological

I-Pharmacodynamic damamycin yeye-antibiotics ye-aminoglycoside, kwaye inefuthe elilinganiselweyo lokuthintela kwiindidi ze-bacilli zegram-negative, ezifana ne-escherichia coli, i-salmonella, i-shigella, i-proteus njalo njalo. Inomdla kwi-streptococcus, pneumococcus, staphylococcus epidermidis kunye ne-mycoplasma ethile (njenge-mycoplasma gallinarum, i-mycoplasma turkey, i-mycoplasma synovialis, njl.). Ubukhulu becala ayinamvakalelo kwi-streptococcus viridis kunye ne-staphylococcus aureus. Ngokuqhelekileyo ayinyangeki kwi-pseudomonas aeruginosa kunye ne-treponemas. Iibhaktheriya zamathumbu zixhathisa kakhulu kwi-megamycin, kodwa azibonakalisi ukumelana ne-streptomycin. I-Lincomycin inomsebenzi olungileyo wokulwa neebhaktheriya ezichasene neebhaktheriya ze-anaerobic, ezifana ne-clostridium, i-peptococcus, i-peptostreptococcus, i-clostridium tetanus, i-clostridium perfringens kunye ne-actinomyces ezininzi. I-Lincomycin isebenza ikakhulu kwi-50s subunit ye-ribosomes yebhaktiriya, echaphazela iprotheni synthesis ngokuthintela ukwandiswa kwekhonkco le-peptide.

I-Pharmacokinetics kuphela i-7% ye-lincomycin ifunnwe emva kokulawulwa kwangaphakathi, kodwa igcina i-concentration ephezulu kwi-gastrointestinal tract. I-tissue concentration yeziyobisi iphantsi kune-serum concentration. Akulula ukungena kwi-cerebrospinal fluid okanye iliso, kwaye izinga lokubopha iprotheni ye-plasma ayiphezulu. Uninzi lwamachiza lukhutshelwa kwi-glomerular filtration kwimo yawo yasekuqaleni. I-bioavailability ye-lincomycin yi-30% ~ 40% kunye nokungeniswa kakubi ekulawuleni ngomlomo. Izinga lokufunxa kunye nesixa se-lincomycin sinokuncitshiswa ngokutyisa okuxutyiweyo. Iinkukhu zanikwa i-50mg yale mveliso (echithwe emanzini okusela) ngekhilogram yobunzima bomzimba iintsuku ezisi-7. Ngethuba lovavanyo, i-plasma lincomycin yafikelela kwi-0.14 μ g / ml, ngelixa i-concentration ye-daguanmycin yayincinci kakhulu. Emva kweentsuku ezi-7 zovavanyo, kudlule i-0.1μg / ml.

Ukusebenzisana kweziyobisi

1. Ngokudibanisa ne-lincomycin, inokunyusa kakhulu umsebenzi we-antibacterial ngokumelene ne-mycoplasma kunye nokwandisa i-antibacterial spectrum.

2. Ukudibanisa kwe-lincomycin kunye ne-anticholinesterase izidakamizwa kunokunciphisa ukusebenza kokugqibela.

3. Idityaniswe ne-erythromycin inefuthe elichasayo.

Isenzo kunye nokusetyenziswa

Amayeza okubulala iintsholongwane. Kwibhaktheriya ye-Gram-negative, ibhaktheriya ye-Gram-positive kunye nosulelo lwe-mycoplasma.

Ukusetyenziswa kunye nomthamo

Isiselo esixutyiweyo: I-100g yale mveliso ixutywe namanzi 200 ~ 300kg yehagu kunye ne-50 ~ 100kg yenkukhu iintsuku ezi-3 ~ 5. Ukutya okuxutyiweyo: 100g yokutya okuxutyiweyo 100kg yeehagu kunye ne-50kg yeenkukhu, isetyenziswe iintsuku ezi-5 ukuya kwezi-7.

Hlwaya ukhathalelo lwempilo: Ukususela kwiintsuku ezisi-7 ngaphambi kokuhanjiswa ukuya kwiintsuku ezisi-7 emva kokuziswa, i-100g yale mveliso ixutywe ne-100kg, okanye i-200kg ngamanzi. Ukhathalelo lwempilo yamantshontsho ehagu: Ngaphambi nasemva kokulunyulwa kunye nenqanaba lenkulisa, i-100g xuba i-100kg, okanye i-200kg yamanzi.