I-Pharmacodynamics semi-synthetic macrolide antibiotics kwiZilwanyana ze-genus temicosin. Yomelele kwi-mycoplasma, kwaye umphumo wayo we-antibacterial ufana ne-tylosin. Iibhaktheriya ezinovakalelo zegram-positive yi-staphylococcus aureus (kuquka i-penicillin-resistant staphylococcus aureus), i-pneumococcus, i-streptococcus, i-anthrax bacillus, i-swineerysipelas, i-listeria, i-clostridium putrefaciens, i-clostridium emphysema njalo njalo. Iibhaktheriya ezibuthathaka zegram-negative yi-haemophilus, i-meningococci, i-pasteurella kwaye kungekudala. Umsebenzi ochasene ne-actinobacillus pleuropneumoniae, i-pasteurella kunye ne-mycoplasma yemfuyo kunye neenkukhu zinamandla kune-tylosin. I-95% yeentlobo ze-pasteurella hemolyticus zazinovelwano kule mveliso.
Ukufakwa ngokukhawuleza kwe-Pharmacokinetic emva kokulawulwa kwangaphakathi, okubonakaliswe ngokungena kwezicubu ezinamandla, umthamo omkhulu wokusabalalisa (umkhulu kune-2l / kg). Ugxininiso luphezulu kwimiphunga, ukuphelisa isiqingatha-ubomi kunokufikelela kwi-1 ~ 2 iintsuku, kwaye ugxininiso lwegazi olusebenzayo lugcinwa ixesha elide.
(1) Indibaniselwano yale mveliso kunye ne-epinephrine inokunyusa ukufa kweehagu.
(2) Inenjongo efanayo njengenye i-macrolides kunye ne-lincoamines, kwaye akufanele isetyenziswe ngexesha elifanayo.
(3) Indibaniselwano ye-β-lactam ibonisa isiphumo esichasayo.
Macrolide antibiotics. Isetyenziselwa ukunyanga i-actinobacillus, i-pasteurella kunye ne-mycoplasma usulelo lwe-porcine pleuropneumoniae.
Ukutya okuxutyiweyo: 1000 ~ 2000g yeehagu kwi-1000kg yokutya kangangeentsuku ezili-15.
(1) Impembelelo eyityhefu yale mveliso kwizilwanyana ikakhulu yinkqubo ye-cardiovascular system, enokubangela i-tachycardia kunye nokunciphisa amandla e-systolic.
(2) Ukuphazamiseka kwesisu esixhomekeke kwi-dose, njengokuhlanza, isifo sohudo, intlungu yesisu, njl., Ngokuqhelekileyo kwenzeka emva kokulawulwa kwangaphakathi.
